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Neurotherapy, Volume - 1st Edition
Newsletter abonnieren. Kontakt E-Mail: service deutscher-apotheker-verlag. Chapter 3. The rostral migratory stream and olfactory system: smell, disease and slippery cells.
The rostral migratory stream RMS pathway: common anatomical features in vertebrates. Chapter 4. Identifying and enumerating neural stem cells: application to aging and cancer. Enumeration of neural stem cells using the neural-colony forming cell assay and a mathematical model. Chapter 5. Transgenic reporter mice as tools for studies of transplantability and connectivity of dopamine neuron precursors in fetal tissue grafts.
Isolation of transplantable midbrain dopamine neurons from stem cell-derived populations. Chapter 6. Chapter 8. Neuroinflammation in spinal cord injury: therapeutic targets for neuroprotection and regeneration. Introduction to spinal cord injury SCI pathology: neuroinflammation in the pathogenesis of secondary injury. Chapter 9. Toll-like receptors in the CNS: implications for neurodegeneration and repair.
Chapter From microsurgery to nanosurgery: how viral vectors may help repair the peripheral nerve. Viral vectors: promising tools to express potentially therapeutic proteins in injured peripheral nerves. Lentiviral vector-mediated overexpression of neurotrophic factors to enhance nerve regeneration.
Failed functional recovery: misrouting of regenerating axons is an important factor. Future perspective: the continuing miniaturization of surgical and diagnostic tools. Gene therapy for neurodegenerative diseases based on lentiviral vectors. Progesterone as a neuroprotective factor in traumatic and ischemic brain injury.
Pharmacological modification of the extracellular matrix to promote regeneration of the injured brain and spinal cord. Moreover, when placed together in to co-culture, dissociated embryonic striatal and mesencephalic cells aggregated spontaneously to form mixed NSs, enhancing the eventual differentiation into dopaminergic neurons from progenitors within these NSs. Conclusion: Therefore, the NSs contained progenitor cells and differentiated neurons and glial cells. In addition, NS culture system can be used to study cellular differentiation in vitro in non-adherent conditions.
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Keywords: Ventral mesencephalon, neurosperes, co-culturing, differentiation. Authors: Ness, Lanitia L. Field-Fote, Edelle C. Abstract: Purpose: Individuals with spinal cord injury SCI often have involuntary, reflex-evoked muscle activity resulting in spasticity.
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Vibration may modulate reflex activity thereby decreasing spasticity. This study suggests feasibility of using whole-body vibration WBV to decrease quadriceps spasticity in individuals with SCI. In addition, differences between immediate immediate post-WBV and delayed delayed post-WBV within-session effects were quantified. Finally, we assessed response differences between subjects who did and those who did not use antispastic agents. Results: There was a significant reduction in quadriceps spasticity after participation in a WBV intervention that persisted for at least eight days.
The WBV intervention was associated with similar changes in quadriceps spasticity in subjects who did and those who did not use antispastic agents. Conclusions: Vibration may be a useful adjunct to training in those with spasticity. Future studies should directly compare the antispastic effects of vibration to those of antispastic agents. Keywords: Spinal reflex, human movement system, rehabilitation, stretch reflex, reflex modulation, Pendulum Test. Tanzer, Lisa Wurster, Robert D.
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Marzo, Sam J. Jones, Kathryn J. Foecking, Eileen M. Abstract: Purpose: The neurotherapeutic effects of nerve electrical stimulation and gonadal steroids have independently been demonstrated. The purpose of this study was to investigate the therapeutic potential of a combinatorial treatment strategy of electrical stimulation and gonadal steroids on peripheral nerve regeneration.
Restorative Neurology and Neuroscience - Volume 27, issue 6
Facial nerve outgrowth was assessed at 4 and 7 days post-axotomy using radioactive labeling. Results: Administration of electrical stimulation alone reduced the estimated delay in sprout formation but failed to accelerate the overall regeneration rate. Combining TP with electrical stimulation, however, maintained the enhanced rate and reduced the sprouting delay. Conclusions: Electrical stimulation and gonadal steroids differentially enhanced regenerative properties.
TP, an aromatizable androgen, augmented regeneration most, suggesting a synergism between androgenic and estrogenic effects. Therapeutically, combining electrical stimulation with gonadal steroids may boost regenerative properties more than the use of either treatment alone.
Keywords: Peripheral nerve injury, regeneration, electrical stimulation, gonadal steroids.
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